Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors

<strong>INTRODUCTION<br></strong> COVID-19 became a global pandemic partially as a result of the lack of easily deployable, broad-spectrum oral antivirals, which complicated its containment. Even endemically, and with effective vaccinations, it will continue to cause acute disease...

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Bibliographic Details
Main Authors: Boby, ML, Fearon, D, Ferla, M, Filep, M, Koekemoer, L, Robinson, MC, Chodera, JD, Lee, AA, London, N, von Delft, A, von Delft, F, Achdout, H, Aimon, A, Alonzi, DS, Arbon, R, Aschenbrenner, JC, Balcomb, BH, Bar-David, E, Barr, H, Ben-Shmuel, A, Bennett, J, Bilenko, VA, Borden, B, Boulet, P, Bowman, GR, Brewitz, L, Brun, J, Bvnbs, S, Calmiano, M, Carbery, A, Carney, DW, Cattermole, E, Chang, E, Chernyshenko, E, Clyde, A, Coffland, JE, Cohen, G, Cole, JC, Contini, A, Cox, L, Croll, TI, Cvitkovic, M, De Jonghe, S, Dias, A, Donckers, K, Dotson, DL, Douangamath, A, Duberstein, S, Dudgeon, T, Fairhead, M, Taylor, JC, Zitzmann, N
Other Authors: COVID Moonshot Consortium
Format: Journal article
Language:English
Published: American Association for the Advancement of Science 2023