Architecture and regulation of the HIV-1 assembly and holding compartment in macrophages.

Productive infection of macrophages is central to HIV-1 pathogenesis. Newly formed virions bud into a tubular membranous compartment that is contiguous with the plasma membrane. However, little is known about the structure of this compartment and its potential regulation by infection. Here we charac...

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Main Authors: Welsch, S, Groot, F, Kräusslich, H, Keppler, O, Sattentau, Q
格式: Journal article
语言:English
出版: 2011