Mechanisms of loss of HLA class I expression on colorectal tumor cells.

For several years this laboratory has studied the expression of HLA class I on established colorectal tumor cell lines and on fresh tumors. We review here the mechanisms by which colorectal tumor cells may lose surface expression of HLA class I molecules. Several independent mechanisms have been ide...

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Bibliographic Details
Main Authors: Browning, M, Petronzelli, F, Bicknell, D, Krausa, P, Rowan, A, Tonks, S, Murray, N, Bodmer, J, Bodmer, W
Format: Journal article
Language:English
Published: 1996