Identifying genes involved in beta cell dysfunction using high-throughput genetic and genomic approaches

<p>Genome-wide association studies have identified >400 signals which are robustly associated with type 2 diabetes (T2D) risk, a large proportion of which are involved in pancreatic beta cell dysfunction. A major barrier to translational insight however is uncertainty over the genes through...

Full description

Bibliographic Details
Main Author: Grotz, AK
Other Authors: Ebner, D
Format: Thesis
Language:English
Published: 2020
Subjects: