Low-input capture-C: A chromosome conformation capture assay to analyze chromatin architecture in small numbers of cells

Chromosome conformation capture (3C) techniques are crucial to understanding tissue-specific regulation of gene expression, but current methods generally require large numbers of cells. This protocol describes two new low-input Capture-C approaches that can generate high-quality 3C interaction profi...

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Detalhes bibliográficos
Main Authors: Oudelaar, AM, Downes, DJ, Davies, JOJ, Hughes, JR
Formato: Journal article
Idioma:English
Publicado em: Bio-Protocol 2017