Low-input capture-C: A chromosome conformation capture assay to analyze chromatin architecture in small numbers of cells

Chromosome conformation capture (3C) techniques are crucial to understanding tissue-specific regulation of gene expression, but current methods generally require large numbers of cells. This protocol describes two new low-input Capture-C approaches that can generate high-quality 3C interaction profi...

Description complète

Détails bibliographiques
Auteurs principaux: Oudelaar, AM, Downes, DJ, Davies, JOJ, Hughes, JR
Format: Journal article
Langue:English
Publié: Bio-Protocol 2017