Chemically modified neoantigen-based immunotherapy for targeting KRASG12C-driven tumors

The clinical efficacy and durability of KRAS<sup>G12C</sup>-targeted therapies are limited by the development of resistance mechanisms. Here, we provide a review of recent KRAS<sup>G12C</sup>-targeted therapy and immunotherapy-unifying strategies that utilize covalently modif...

Полное описание

Библиографические подробности
Главные авторы: Abdel Mouti, M, Pauklin, S
Формат: Journal article
Язык:English
Опубликовано: Cell Press 2023