Chemically modified neoantigen-based immunotherapy for targeting KRASG12C-driven tumors

The clinical efficacy and durability of KRAS<sup>G12C</sup>-targeted therapies are limited by the development of resistance mechanisms. Here, we provide a review of recent KRAS<sup>G12C</sup>-targeted therapy and immunotherapy-unifying strategies that utilize covalently modif...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Abdel Mouti, M, Pauklin, S
Format: Journal article
Sprache:English
Veröffentlicht: Cell Press 2023