Functional regulation of p73 and p63: development and cancer.

Functional regulation of p73 and p63: development and cancer.

The transcription factor and tumour suppressor p53 and its two homologues p63 and p73 form a family of proteins. p63 and p73 show much greater molecular complexity than p53 because they are expressed both as multiple alternatively spliced C-terminal isoforms, and as N-terminally deleted, dominant-ne...

Полное описание

Библиографические подробности
Главные авторы:	Melino, G, Lu, X, Gasco, M, Crook, T, Knight, R
Формат:	Journal article
Язык:	English
Опубликовано:	2003

Схожие документы

P63 and P73 Activation in Cancers with p53 Mutation
по: Bi-He Cai, и др.
Опубликовано: (2022-06-01)

Distinct p63 and p73 Protein Interactions Predict Specific Functions in mRNA Splicing and Polyploidy Control in Epithelia
по: Julian M. Rozenberg, и др.
Опубликовано: (2020-12-01)

p63 and p73 transcriptionally regulate genes involved in DNA repair.
по: Yu-Li Lin, и др.
Опубликовано: (2009-10-01)

p63 and p73 Transcriptionally Regulate Genes Involved in DNA Repair
по: Lin, Yu-Li, и др.
Опубликовано: (2010)

Mechanism of TAp73 inhibition by ΔNp63 and structural basis of p63/p73 hetero-tetramerization.
по: Gebel, J, и др.
Опубликовано: (2016)

Retraction: p63 and p73 Transcriptionally Regulate Genes Involved in DNA Repair.
по: PLOS Genetics Editors
Опубликовано: (2023-03-01)

Biochemical and structural studies of ASPP proteins reveal differential binding to p53, p63, and p73.
по: Robinson, R, и др.
Опубликовано: (2008)

A família do p53: aspectos estruturais e funcionais do p73 e do p63 The p53 family: structural and functional aspects of p73 and p63
по: Alfredo Ribeiro-Silva, и др.
Опубликовано: (2003-06-01)

Dynamic expression of the p53 family members p63 and p73 in the mouse and human telencephalon during development and in adulthood.
по: Hernández-Acosta, N, и др.
Опубликовано: (2011)

Dynamic expression of the p53 family members p63 and p73 in the mouse and human telencephalon during development and in adulthood
по: Hernández-Acosta, N, и др.
Опубликовано: (2011)

The tumor suppressors p53, p63, and p73 are regulators of microRNA processing complex.
по: Lakshmanane Boominathan
Опубликовано: (2010-05-01)

Role of p63 and the Notch pathway in cochlea development and sensorineural deafness.
по: Terrinoni, A, и др.
Опубликовано: (2013)

Polymorphisms in the p63 and p73 genes are associated with ovarian cancer risk and clinicopathological variables
по: Guan Xiao, и др.
Опубликовано: (2012-10-01)

Structural evolution of p53, p63, and p73: implication for heterotetramer formation.
по: Joerger, A, и др.
Опубликовано: (2009)

Oncogenic p53 triggers amyloid aggregation of p63 and p73 liquid droplets
по: Elaine C. Petronilho, и др.
Опубликовано: (2024-09-01)

Tissue-specific expression of p73 and p63 isoforms in human tissues
по: Clayton B. Marshall, и др.
Опубликовано: (2021-07-01)

Functional Diversification after Gene Duplication: Paralog Specific Regions of Structural Disorder and Phosphorylation in p53, p63, and p73.
по: Helena G Dos Santos, и др.
Опубликовано: (2016-01-01)

p53 polymorphism influences response in cancer chemotherapy via modulation of p73-dependent apoptosis.
по: Bergamaschi, D, и др.
Опубликовано: (2003)

p73 and p63 sustain cellular growth by transcriptional activation of cell cycle progression genes.
по: Lefkimmiatis, K, и др.
Опубликовано: (2009)

The p53 family member p73 in the regulation of cell stress response
по: Julian M. Rozenberg, и др.
Опубликовано: (2021-11-01)

p63 is a promising marker in the diagnosis of unusual skin cancer
по: Smirnov, A, и др.
Опубликовано: (2019)

DARPins detect the formation of hetero-tetramers of p63 and p73 in epithelial tissues and in squamous cell carcinoma
по: Alexander Strubel, и др.
Опубликовано: (2023-10-01)

Role of p63 and p73 isoforms on the cell death in patients with hepatocellular carcinoma submitted to orthotopic liver transplantation.
по: Raúl González, и др.
Опубликовано: (2017-01-01)

BRD4 sustains p63 transcriptional program in keratinocytes
по: E. Foffi, и др.
Опубликовано: (2024-11-01)

Mechanisms of Functional Pleiotropy of p73 in Cancer and Beyond
по: Stella Logotheti, и др.
Опубликовано: (2021-09-01)

Revisiting the Dimensions of Knowledge Management Orientation Behavior in Indonesia Creative Industry (P.63-73)
по: Ananda Sabil Hussein, и др.
Опубликовано: (2017-02-01)

STAT3 and p63 in the Regulation of Cancer Stemness
по: Shixiong Wei, и др.
Опубликовано: (2022-08-01)

Dual Role of p73 in Cancer Microenvironment and DNA Damage Response
по: Julian M. Rozenberg, и др.
Опубликовано: (2021-12-01)

Role of p73 Dinucleotide Polymorphism in Prostate Cancer and p73 Protein Isoform Balance
по: L. Michael Carastro, и др.
Опубликовано: (2014-01-01)

ZEB1 links p63 and p73 in a novel neuronal survival pathway rapidly induced in response to cortical ischemia.
по: Thai Bui, и др.
Опубликовано: (2009-01-01)

Different regulation of limb development by p63 transcript variants.
по: Manabu Kawata, и др.
Опубликовано: (2017-01-01)

Genome-wide mapping indicates that p73 and p63 co-occupy target sites and have similar dna-binding profiles in vivo.
по: Annie Yang, и др.
Опубликовано: (2010-07-01)

p63: A Master Regulator at the Crossroads Between Development, Senescence, Aging, and Cancer
по: Lakshana Sruthi Sadu Murari, и др.
Опубликовано: (2025-01-01)

The dual role of p63 in cancer
по: Yongfeng Xu, и др.
Опубликовано: (2023-04-01)

The p63 C-terminus is essential for murine oocyte integrity
по: Lena, AM, и др.
Опубликовано: (2021)

p63 orchestrates serine and one carbon metabolism enzymes expression in head and neck cancer
по: Angela Cappello, и др.
Опубликовано: (2023-11-01)

Epigenetic modification in the expression of p73 p73 - epigenetic target for anticancer therapy
по: Faiza Naseer, и др.
Опубликовано: (2019-07-01)

ZNF185 is a p63 target gene critical for epidermal differentiation and squamous cell carcinoma development
по: Smirnov, A, и др.
Опубликовано: (2018)

Transcription factor p73 regulates Th1 differentiation
по: Min Ren, и др.
Опубликовано: (2020-03-01)

Roles of p63 in epidermal development and tumorigenesis
по: Jeng-Yuan Yao, и др.
Опубликовано: (2012-12-01)