DNA repair at the gene level in trichothiodystrophy cells
Cells from trichothiodystrophy (TTD) group 3 patients are non-hypersensitive to uv irradiation. These cells perform normal genome repair of pyrimidine dimers but fail to excise 6-4 photoproducts and concomitantly, are unable to restore RNA synthesis levels following uv irradiation. This pointed to a...
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Universiti Kebangsaan Malaysia
2000
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