DNA repair at the gene level in trichothiodystrophy cells

Cells from trichothiodystrophy (TTD) group 3 patients are non-hypersensitive to uv irradiation. These cells perform normal genome repair of pyrimidine dimers but fail to excise 6-4 photoproducts and concomitantly, are unable to restore RNA synthesis levels following uv irradiation. This pointed to a...

Полное описание

Библиографические подробности
Главные авторы: Nathan , Sheila, Mayne, Lynne
Формат: Статья
Опубликовано: Universiti Kebangsaan Malaysia 2000