Application of cyrotechnology techniques: a case study for the production, purification and characterization of humanized antibody secreted by NSO transfectoma
Humanized monoclonal antibodies are widely used for diagnosis and treatment of cancer due to their reduced immunogenicity and high specificity. These valuable biopharmaceuticals are produced using mammalian cells which often require serum when cultured in vitro. Since the use of serum involves many...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Malaysian Society for Molecular Biology and Biotechnology
2011
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Subjects: | |
Online Access: | http://eprints.um.edu.my/10093/1/Application_of_cyrotechnology_techniques.pdf |