Application of cyrotechnology techniques: a case study for the production, purification and characterization of humanized antibody secreted by NSO transfectoma

Humanized monoclonal antibodies are widely used for diagnosis and treatment of cancer due to their reduced immunogenicity and high specificity. These valuable biopharmaceuticals are produced using mammalian cells which often require serum when cultured in vitro. Since the use of serum involves many...

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Bibliographic Details
Main Authors: Cheah, S.H., Dharshanan, S., Chong, H., Zamrod, Z.
Format: Article
Language:English
Published: Malaysian Society for Molecular Biology and Biotechnology 2011
Subjects:
Online Access:http://eprints.um.edu.my/10093/1/Application_of_cyrotechnology_techniques.pdf