Inhibition of Raf-MEK-ERK and Hypoxia pathways by Phyllanthus prevents metastasis in human lung (A549) cancer cell line

Background: Lung cancer constitutes one of the malignancies with the greatest incidence and mortality rates with 1.6 million new cases and 1.4 million deaths each year. Prognosis remains poor due to deleterious development of multidrug resistance resulting in less than 15 lung cancer patients reachi...

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Bibliografiske detaljer
Main Authors: Lee, S.H., Jaganath, I.B., Manikam, R., Sekaran, S.D.
Format: Article
Sprog:English
Udgivet: BioMed Central 2013
Fag:
Online adgang:http://eprints.um.edu.my/10628/1/Lee-2013-Inhibition_of_Raf-ME.pdf