Acridone alkaloids from Glycosmis chlorosperma as DYRK1A inhibitors
Two new acridone alkaloids, chlorospermines A and B (1 and 2), were isolated from the stem bark of Glycosmis chlorosperma, together with the known atalaphyllidine (3) and acrifoline (4), by means of bioguided isolation using an in vitro enzyme assay against DYRK1A. Acrifoline (4) and to a lesser ext...
| Main Authors: | , , , , , , , |
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| Format: | Article |
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American Chemical Society
2014
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