Different chemically substituted chitooligosaccharides inhibit beta-secretase activity

Chitooligosaccharide or COS is a kind of oligosaccharide that is an integral part of the nervous system. COS is synthesized by chemical substitution and derived AE-COS, DEAE-COS and DMAE-COS that are being shown on IC(50) value. AE-COS and DMAE-COS exhibited four fold less inhibition than DEAE-COS....

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Bibliographic Details
Main Authors: Ahmed, A.B.A., Yoon, N.Y., Taha, R.M., Kim, S.K.
Format: Article
Language:English
Published: 2011
Subjects:
Online Access:http://eprints.um.edu.my/10716/1/Different_chemically_substituted_chitooligosaccharides_inhibit_beta-secretase_activity.PDF