Intravenous salbutamol for external cephalic version
Objective: To evaluate the success of external cephalic version (ECV) using an adjusted bolus dose intravenous salbutamol compared with no tocolysis. Methods: An open-label randomized study of 114 women with a term breech fetus randomized to receive either an intravenous bolus dose of 0.1 mg salbuta...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
2009
|
| Subjects: | |
| Online Access: | http://eprints.um.edu.my/10850/1/Intravenous_salbutamol_for_external_cephalic_version.pdf |
| _version_ | 1825719924273709056 |
|---|---|
| author | Vani, S. Lau, S.Y. Lim, B.K. Omar, S.Z. Tan, P.C. |
| author_facet | Vani, S. Lau, S.Y. Lim, B.K. Omar, S.Z. Tan, P.C. |
| author_sort | Vani, S. |
| collection | UM |
| description | Objective: To evaluate the success of external cephalic version (ECV) using an adjusted bolus dose intravenous salbutamol compared with no tocolysis. Methods: An open-label randomized study of 114 women with a term breech fetus randomized to receive either an intravenous bolus dose of 0.1 mg salbutarnol with further boluses every 5 minutes, as required, before commencing ECV, or no tocolysis. Primary outcomes were successful ECV and rate of cesarean delivery. Results: Salbutamol tocolysis resulted in a higher rate of successful ECV compared with no tocolysis (70.2 40/57 vs 36.8% 21/57; RR 1.9, 95% CI 1.3-2.8; P<0.001). Cesarean delivery rate was lower in the salbutamol group compared with the control group (31.6% 18/57 vs 63.2% 36/57; RR 0.5. 95% CI 0.3-0.8: P=0.001). Salbutamol dose ranged from 0.1-0.4 mg and Outcome was not related to dose. Conclusion: Adjusted dose intravenous salbutamol tocolysis prior to ECV increases its success rate and reduces the cesarean delivery rate. (C) 2008 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved. |
| first_indexed | 2024-03-06T05:27:09Z |
| format | Article |
| id | um.eprints-10850 |
| institution | Universiti Malaya |
| language | English |
| last_indexed | 2024-03-06T05:27:09Z |
| publishDate | 2009 |
| record_format | dspace |
| spelling | um.eprints-108502014-07-16T00:04:52Z http://eprints.um.edu.my/10850/ Intravenous salbutamol for external cephalic version Vani, S. Lau, S.Y. Lim, B.K. Omar, S.Z. Tan, P.C. R Medicine RG Gynecology and obstetrics Objective: To evaluate the success of external cephalic version (ECV) using an adjusted bolus dose intravenous salbutamol compared with no tocolysis. Methods: An open-label randomized study of 114 women with a term breech fetus randomized to receive either an intravenous bolus dose of 0.1 mg salbutarnol with further boluses every 5 minutes, as required, before commencing ECV, or no tocolysis. Primary outcomes were successful ECV and rate of cesarean delivery. Results: Salbutamol tocolysis resulted in a higher rate of successful ECV compared with no tocolysis (70.2 40/57 vs 36.8% 21/57; RR 1.9, 95% CI 1.3-2.8; P<0.001). Cesarean delivery rate was lower in the salbutamol group compared with the control group (31.6% 18/57 vs 63.2% 36/57; RR 0.5. 95% CI 0.3-0.8: P=0.001). Salbutamol dose ranged from 0.1-0.4 mg and Outcome was not related to dose. Conclusion: Adjusted dose intravenous salbutamol tocolysis prior to ECV increases its success rate and reduces the cesarean delivery rate. (C) 2008 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved. 2009 Article PeerReviewed application/pdf en http://eprints.um.edu.my/10850/1/Intravenous_salbutamol_for_external_cephalic_version.pdf Vani, S. and Lau, S.Y. and Lim, B.K. and Omar, S.Z. and Tan, P.C. (2009) Intravenous salbutamol for external cephalic version. International Journal of Gynecology & Obstetrics, 104 (1). pp. 28-31. ISSN 0020-7292, DOI https://doi.org/10.1016/j.ijgo.2008.08.014 <https://doi.org/10.1016/j.ijgo.2008.08.014>. http://www.sciencedirect.com/science/article/pii/S0020729208003822 10.1016/j.ijgo.2008.08.014 |
| spellingShingle | R Medicine RG Gynecology and obstetrics Vani, S. Lau, S.Y. Lim, B.K. Omar, S.Z. Tan, P.C. Intravenous salbutamol for external cephalic version |
| title | Intravenous salbutamol for external cephalic version |
| title_full | Intravenous salbutamol for external cephalic version |
| title_fullStr | Intravenous salbutamol for external cephalic version |
| title_full_unstemmed | Intravenous salbutamol for external cephalic version |
| title_short | Intravenous salbutamol for external cephalic version |
| title_sort | intravenous salbutamol for external cephalic version |
| topic | R Medicine RG Gynecology and obstetrics |
| url | http://eprints.um.edu.my/10850/1/Intravenous_salbutamol_for_external_cephalic_version.pdf |
| work_keys_str_mv | AT vanis intravenoussalbutamolforexternalcephalicversion AT lausy intravenoussalbutamolforexternalcephalicversion AT limbk intravenoussalbutamolforexternalcephalicversion AT omarsz intravenoussalbutamolforexternalcephalicversion AT tanpc intravenoussalbutamolforexternalcephalicversion |