Nickel(II) Complex of Polyhydroxybenzaldehyde N4-Thiosemicarbazone Exhibits Anti-Inflammatory Activity by Inhibiting NF-κB Transactivation

Background The biological properties of thiosemicarbazone have been widely reported. The incorporation of some transition metals such as Fe, Ni and Cu to thiosemicarbazone complexes is known to enhance its biological effects. In this study, we incorporated nickel(II) ions into thiosemicarbazone w...

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Bibliographic Details
Main Authors: Shawish, H.B., Wong, W.Y., Wong, Y.L., Loh, S.W., Looi, C.Y., Hassandarvish, P., Phan, A.Y.L., Wong, W.F., Wang, H., Paterson, I.C., Kwee, C.
Format: Article
Language:English
Published: Public Library of Science 2014
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Online Access:http://eprints.um.edu.my/11039/1/00004028_106610.pdf