Large BRCA1 and BRCA2 genomic rearrangements in Malaysian high risk breast-ovarian cancer families
Early studies of genetic predisposition due to the BRCA1 and BRCA2 genes have focused largely on sequence alterations, but it has now emerged that 4-28% of inherited mutations in the BRCA genes may be due to large genomic rearrangements of these genes. However, to date, there have been relatively fe...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
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Kluwer (now part of Springer)
2010
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| Subjects: |