Population pharmacokinetics of vancomycin in premature Malaysian neonates: identification of predictors for dosing determination

The present study determined the pharmacokinetic profile of vancomycin in premature Malaysian infants. A one-compartment infusion model with first-order elimination was fitted to serum vancomycin concentration data (n = 835 points) obtained retrospectively from the drug monitoring records of 116 pre...

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Bibliographic Details
Main Authors: Lo, Y., van Hasselt, J.G.C., Heng, S., Lim, C., Lee, T., Charles, B.G.
Format: Article
Published: American Society for Microbiology 2010
Subjects: