Inhibition of quorum sensing-controlled virulence factors and biofilm formation in pseudomonas aeruginosa by culture extract from novel bacterial species of paenibacillus using a rat model of chronic lung infection
Quorum sensing (QS) is a key regulator of virulence factors and biofilm formation in Gram-negative bacteria such as Pseudomonas aeruginosa. Microorganisms that inhabit soil are of strategic importance in the discovery of compounds with anti-QS properties. The objective of the study was to test the c...
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Hindawi Publishing Corporation
2015
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