The impact of antibody/epitope affinity strength on the sensitivity of electrochemical immunosensors for detecting small molecules
A displacement immunoassay involves having a labelled analogue of the analyte (the epitope) already bound to the antibody. The presence of the analyte causes a competition for antibodies, and some of the antibodies dissociates from the epitope so that it can bind with the analyte. Herein, the i...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Springer Verlag (Germany)
2013
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Subjects: | |
Online Access: | http://eprints.um.edu.my/15519/1/Analytical_and_Bioanalytical_Chemistry_405%282013%293889-3898_%28post-print_version%29.pdf |