Local application of osteoprotegerin-chitosan gel in critical-sized defects in a rabbit model

Background. Osteoprotegerin (OPG) is used for the systemic treatment of bone diseases although it has many side effects. The aim of this study was to investigate a newly formulated OPG-chitosan gel fort local application to repair bone defects. Recent studies have reported that immunodetection of os...

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Bibliographic Details
Main Authors: Jayash, S.N., Hashim, Najihah Mohd, Misran, Misni, Baharuddin, Nor Adinar
Format: Article
Language:English
Published: PeerJ 2017
Subjects:
Online Access:http://eprints.um.edu.my/17790/1/3513.pdf