Interaction between irbesartan, peroxisome proliferator-activated receptor (PPAR-γ), and adiponectin in the regulation of blood pressure and renal function in spontaneously hypertensive rats

Adiponectin exerts vasodilatory effects. Irbesartan, an angiotensin receptor blocker, possesses partial peroxisome proliferator-activated receptor gamma (PPAR-γ) agonist activity and increases circulating adiponectin. This study explored the effect of irbesartan alone and in combination with adipone...

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Bibliographic Details
Main Authors: Afzal, S., Sattar, M.A., Johns, E.J., Abdulla, M.H., Akhtar, S., Hashmi, F., Abdullah, N.A.
Format: Article
Published: Springer Verlag (Germany) 2016
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