Peripheral loss of CD8+CD161++TCRVα7·2+ mucosal-associated invariant T cells in chronic hepatitis C virus-infected patients

Background: Mucosal-associated invariant T (MAIT) cells play an important role in innate host defence. MAIT cells appear to undergo exhaustion and are functionally weakened in chronic viral infections. However, their role in chronic hepatitis C virus (HCV) infection remains unclear. Materials and me...

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Main Authors: Barathan, M., Mohamed, R., Vadivelu, J., Chang, L.Y., Saeidi, A., Yong, Y.K., Ravishankar Ram, M., Gopal, K., Velu, V., Larsson, M., Shankar, E.M.
Format: Article
Published: Blackwell Publishing 2016
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