Activation of Akt and the signaling of phosphorylated Akt in the L5 dorsal root ganglia in aging rats
Introduction Protein kinase B (PKB)/Akt is a kinase that is responsive towards insulin-like growth factor (IGF-1) and nerve growth factor (NGF). Detected in the cytosol, Akt is activated by phosphorylation at Thr308/Ser473 residue. The phosphorylated Akt (pAkt) is translocated into the nucleus via t...
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Elsevier
2017
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