Sustainable Syntheses of (−)-Jerantinines A & E and Structural Characterisation of the Jerantinine-Tubulin Complex at the Colchicine Binding Site

Sustainable Syntheses of (−)-Jerantinines A & E and Structural Characterisation of the Jerantinine-Tubulin Complex at the Colchicine Binding Site

The jerantinine family of Aspidosperma indole alkaloids from Tabernaemontana corymbosa are potent microtubule-Targeting agents with broad spectrum anticancer activity. The natural supply of these precious metabolites has been significantly disrupted due to the inclusion of T. corymbosa on the endang...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Smedley, C.J., Stanley, P.A., Qazzaz, M.E., Prota, A.E., Olieric, N., Collins, H., Eastman, H., Barrow, A.S., Lim, K.H., Kam, T.S., Smith, B.J., Duivenvoorden, H.M., Parker, B.S., Bradshaw, T.D., Steinmetz, M.O., Moses, J.E.
Aineistotyyppi: Artikkeli
Kieli:English
Julkaistu: Nature Publishing Group 2018
Aiheet:
Q Science (General)
R Medicine
Linkit:http://eprints.um.edu.my/18983/1/Sustainable_Syntheses_of_%28-%29-Jerantinines_A_%26_e_and_Structural_Characterisation_of_the_Jerantinine-Tubulin_Complex_at_the_Colchicine_Binding_Site.pdf

Internet

http://eprints.um.edu.my/18983/1/Sustainable_Syntheses_of_%28-%29-Jerantinines_A_%26_e_and_Structural_Characterisation_of_the_Jerantinine-Tubulin_Complex_at_the_Colchicine_Binding_Site.pdf

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