Persistent infection due to a small-colony variant of Burkholderia pseudomallei leads to PD-1 upregulation on circulating immune cells and mononuclear infiltration in viscera of experimental BALB/c mice
Background: Melioidosis is a neglected tropical disease endemic across South East Asia and Northern Australia. The etiological agent, Burkholderia pseudomallei (B.pseudomallei), is a Gram-negative, rod-shaped, motile bacterium residing in the soil and muddy water across endemic regions of the tropic...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science
2017
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| Subjects: | |
| Online Access: | http://eprints.um.edu.my/19034/1/Persistent_infection_due_to_a_small-colony_variant_of_Burkholderia_pseudomallei_leads_to_PD-1_upregulation_on_circulating_immune_cells_and_mononuclear_infiltration.pdf |