Synthesized flavanoid-derived ligand reduced dengue virus type-2 replication in vitro

Objective To investigate the antiviral property of a lead ligand, YK51 that was synthesized based on the flavanoid of a natural product toward dengue virus type-2 (DENV2) replication. Methods cRNA was isolated from HepG2 cells inoculated with 1 000 median tissue culture infective dose of DENV2 and t...

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Bibliographic Details
Main Authors: Muhamad, M., Lee, Y.K., Rahman, N.A., Yusof, R.
Format: Article
Published: Elsevier 2017
Subjects: