Antiproliferation effect of imatinib mesylate on MCF7, T-47D tumorigenic and MCF 10A nontumorigenic breast cell lines via PDGFR-β, PDGF-BB, c-Kit and SCF genes

Recent cancer molecular therapies are targeting main functional molecules to control applicable process of cancer cells. Attractive targets are established by receptor tyrosine kinases, such as platelet-derived growth factor receptors (PDGFRs) and c-Kit as mostly irregular signaling, which is due to...

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Bibliographic Details
Main Authors: Kadivar, A., Kamalidehghan, B., Javar, H.A., Karimi, B., Sedghi, R., Noordin, M.I.
Format: Article
Published: Dove Medical Press 2017
Subjects: