Mechanisms of action and in vivo antibacterial efficacy assessment of five novel hybrid peptides derived from Indolicidin and Ranalexin against Streptococcus pneumoniae

Background. Antimicrobial peptides (AMPs) are of great potential as novel antibiotics for the treatment of broad spectrum of pathogenic microorganisms including resistant bacteria. In this study, the mechanisms of action and the therapeutic efficacy of the hybrid peptides were examined. Methods. TEM...

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Bibliographic Details
Main Authors: Jindal, H.M., Zandi, K., Ong, Kien Chai, Velayuthan, Rukumani Devi, Rasid, S.M., Samudi, Chandramathi, Sekaran, Shamala Devi
Format: Article
Published: PeerJ 2017
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