Renal targeting potential of a polymeric drug carrier, poly-L-glutamic acid, in normal and diabetic rats
Background and purpose: Poly-l-glutamic acid (PG) has been used widely as a carrier to deliver anticancer chemotherapeutics. This study evaluates PG as a selective renal drug carrier. Experimental approach: 3H-deoxycytidine-labeled PGs (17 or 41 kDa) and 3H-deoxycytidine were administered intravenou...
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article |
| Published: |
Dove Medical Press
2017
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