PI3K/mTORC2 regulates TGF-β/Activin signalling by modulating Smad2/3 activity via linker phosphorylation
Crosstalk between the phosphatidylinositol 3-kinase (PI3K) and the transforming growth factor-β signalling pathways play an important role in regulating many cellular functions. However, the molecular mechanisms underpinning this crosstalk remain unclear. Here, we report that PI3K signalling antagon...
| Autori principali: | , , , , , , |
|---|---|
| Natura: | Articolo |
| Pubblicazione: |
Nature Publishing Group
2015
|
| Soggetti: |