Zebrafish embryonic development-interfering macrolides from Streptomyces californicus impact growth and mitochondrial function in human colorectal cancer cells

Microorganisms are now recognized as a keysource of medicine. In this study, we aim to identify and characterize target-specific inhibitors from actinobacteria using zebrafish embryo developmental defect as readouts. From our preliminary screen, we evaluated 176 Malaysian actinobacteria extracts and...

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Bibliographic Details
Main Authors: Tan, Pei Jean, Lau, Beng Fye, Krishnasamy, Getha, Ng, Mei Fong, Husin, Lili Sahira, Ruslan, Nur Faizah, Song, D.S.S., Velaithan, Vithya, Okuda, Kazuhide Shaun, Patel, Vyomesh
Format: Article
Published: Elsevier 2018
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