Synthesis of 1,3-benzoxazines Based on 2,4,4-trimethyl-7,2’,4’-trihydroxy Flavan: Antibacterial, Anti-inflammatory, Cyclooxygenase-2 Inhibition and Molecular Modelling Studies

Background: In the present study, the formation of 2, 4, 4-trimethyl-7,2’4’-trihydroxy flavan has been used as the key feature for the formation of new 1,3-benzoxazines. This reaction was carried out via Mannich-condensation reaction, the 7-hydroxy group of flavan was reacted with different primary...

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Bibliographic Details
Main Authors: Mohammed, Issam Ahmed, Ahmed, Mahmood, Ikram, Rabia, Muddassar, Muhammad, Qadir, Muhammad Abdul, Awang, Khalijah
Format: Article
Published: Bentham Science Publishers 2018
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