The mechanism of formation, structure and physiological relevance of covalent hemoglobin attachment to the erythrocyte membrane
Covalent hemoglobin binding to membranes leads to band 3 (AE1) clustering and the removal of erythrocytes from the circulation; it is also implicated in blood storage lesions. Damaged hemoglobin, with the heme being in a redox and oxygen-binding inactive hemichrome form, has been implicated as the b...
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Format: | Article |
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Elsevier
2017
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