Development of an Alkaloid-Pyrone Annulation: Synthesis of Pleiomaltinine

Odd Couple: A method for the synthesis of alkaloid-pyrones using a novel pyrone annulation of β-carbolines and indoles with 3-siloxy-4-pyrones is reported. The approach has enabled synthesis of the unusual alkaloid-pyrone pleiomaltinine from the plant-derived indole-alkaloid pleiocarpamine (see Sche...

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Bibliographic Details
Main Authors: Ziegler, Robert E., Tan, Shin Jowl, Kam, Toh Seok, Porco, John A.
Format: Article
Published: John Wiley & Sons 2012
Subjects: