Senescent HUVECs-secreted exosomes trigger endothelial barrier dysfunction in young endothelial cells
Accumulation of senescent endothelial cells can cause endothelium dysfunction which eventually leads to agerelated vascular disorders. The senescent-associated secretory phenotype (SASP) cells secrete a plethora of soluble factors that negatively influence the surrounding tissue microenvironment. Th...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Published: |
Leibniz Research Centre for Working Environment and Human Factors
2019
|
| Subjects: |