Senescent HUVECs-secreted exosomes trigger endothelial barrier dysfunction in young endothelial cells
Accumulation of senescent endothelial cells can cause endothelium dysfunction which eventually leads to agerelated vascular disorders. The senescent-associated secretory phenotype (SASP) cells secrete a plethora of soluble factors that negatively influence the surrounding tissue microenvironment. Th...
| Egile Nagusiak: | , , , , , |
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| Formatua: | Artikulua |
| Argitaratua: |
Leibniz Research Centre for Working Environment and Human Factors
2019
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| Gaiak: |