Biophysical and computational approaches to unravel the molecular interaction mechanism of bromodeoxyuridine, a proliferative marker with human serum albumin

Abstract: The interaction of a nucleoside analogue bromodeoxyuridine (BrdU) with human serum albumin (HSA) was studied to investigate the binding phenomenon and analyse the protein conformation upon BrdU binding. Multiple spectroscopic techniques, viz. intrinsic and 3-D fluorescence, UV–Vis absorpti...

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Bibliographic Details
Main Authors: Roslan, Amira Adlin, Kandandapani, Salanee, Ridzwan, Nor Farrah Wahidah, Mohamad, Saharuddin, Tayyab, Saad
Format: Article
Published: Springer Verlag 2019
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