Actions of three clostridial IgA proteases on distinct forms of immunoglobulin A molecules

Three bacterial species of Clostridium (septicum, tertium and sporogenes) were identified to produce extracellular proteases cleaving IgA to Fab and Fc fragments, as demonstrated by SDS-PAGE and immunoelectrophoretic procedures. These enzymes acted on monometric IgA1 paraproteins and normal serum Ig...

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Bibliographic Details
Main Authors: Hashim, Onn Haji, Hassan, H.
Format: Article
Published: 1991
Subjects: