Cardiovascular activity of Labdane Diterpenes from andrographis paniculata in isolated rat hearts

The dichloromethane (DCM) extract of Andrographis paniculata Nees was tested for cardiovascular activity. The extract significantly reduced coronary perfusion pressure by up to 24.5 ± 3.0 mm Hg at a 3 mg dose and also reduced heart rate by up to 49.5 ± 11.4 beats/minute at this dose. Five labdane di...

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Bibliographic Details
Main Authors: Awang, Khalijah, Abdullah, N.H., Hadi, A.H., Su Fong, Y.
Format: Article
Language:English
Published: Hindawi Publishing Corporation 2012
Subjects:
Online Access:http://eprints.um.edu.my/3168/1/1.pdf