Interaction of Hb South Florida (codon 1; GTG -> ATG) and HbE, with beta-thalassemia (IVS1-1; G -> A): expression of different clinical phenotypes

Interactions of different hemoglobin variants with thalassemia alleles can result in various clinical phenotypes. HbE-beta-thalassemia generally manifests with severe anemia where individuals exhibit beta-thalassemia major with regular blood transfusions or beta-thalassemia intermedia with periodic...

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Bibliographic Details
Main Authors: Tan, J., Tan, K.L., Omar, K.Z., Chan, L.L., Wee, Y.C., George, E.
Format: Article
Language:English
Published: 2009
Subjects:
Online Access:http://eprints.um.edu.my/3712/1/Interaction_of_Hb_South_Florida_%28codon_1%3B_GTG%E2%86%92ATG%29_and_HbE%2C_with_%CE%B2-thalassemia.pdf