Mutation analysis of the BRCA1 gene in Malaysian breast cancer patients

Thirty patients with early onset breast cancer or familial breast cancer from Malaysia were analysed for germline mutation in the early onset breast cancer I gene (BRCA1). Direct sequencing of the entire coding region of BRCA1 identified a frameshift mutation, c.5447-5448insC (insC5447) (codon 1776...

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Bibliographic Details
Main Authors: Balraj, P., Khoo, A.S.B., Volpi, L., Tan, J.A.M.A., Nair, S., Abdullah, H.
Format: Article
Language:English
Published: Stamford Publishing Pte Ltd / Singapore Medical Association 2002
Subjects:
Online Access:http://eprints.um.edu.my/3725/1/Mutational_analysis_of_the_BRCA1_gene_in.pdf