Epigenetic silencing of CYP24 in the tumor microenvironment

Calcitriol (1,25 dihydroxycholecalciferol) has significant anti-tumor activity in vitro and in vivo in a number of tumor model systems. We developed a system for isolation of fresh endothelial cells from tumors and Matrigel environments which demonstrate that CYP24, the catabolic enzyme involved in...

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Main Authors: Johnson, C.S., Chung, I., Trump, D.L.
格式: 文件
语言:English
出版: 2010
主题:
在线阅读:http://eprints.um.edu.my/5077/1/Johnson-2010-Epigenetic_silencing.pdf