Epigenetic silencing of CYP24 in the tumor microenvironment
Calcitriol (1,25 dihydroxycholecalciferol) has significant anti-tumor activity in vitro and in vivo in a number of tumor model systems. We developed a system for isolation of fresh endothelial cells from tumors and Matrigel environments which demonstrate that CYP24, the catabolic enzyme involved in...
Main Authors: | , , |
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格式: | 文件 |
语言: | English |
出版: |
2010
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主题: | |
在线阅读: | http://eprints.um.edu.my/5077/1/Johnson-2010-Epigenetic_silencing.pdf |