A revisit into the Den2 NS2B/NS3 virus protease homology model: Structural verification and comparison with crystal structure of HCV NS3/4A and Den2 NS3
Although the crystal structure of DEN2 NS3 serine protease has been reported, the proteolytic mechanism of this enzyme in the presence of NS2B as co-factor which greatly enhances its activity is not well-understood. Using the homology model of DEN2 NS3 co-complexed with NS2B co-factor based on HCV N...
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| Format: | Article |
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Faculty of Science, University of Malaya
2006
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