Inhibitory activity of cyclohexenyl chalcone derivatives and flavonoids of fingerroot, Boesenbergia rotunda (L.), towards dengue-2 virus NS3 protease

Boesenbergia rotunda (L.) cyclohexenyl chalcone derivatives, 4-hydroxypanduratin A and panduratin A, showed good competitive inhibitory activities towards dengue 2 virus NS3 protease with the K-i values of 21 and 25 mu M, respectively, whilst those of pinostrobin and cardamonin were observed to be n...

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Bibliographic Details
Main Authors: Tan, Siew Kiat, Pippen, Richard, Yusof, Rohana, Ibrahim, Halijah, Khalid, Norzulaani, Abd Rahman, Noorsaadah
Format: Article
Language:English
Published: Elsevier 2006
Subjects:
Online Access:http://eprints.um.edu.my/7140/1/Kiat-2006-Inhibitory_activity.pdf