Kinetics and mechanism of large rate enhancement in the Alkaline Hydrolysis of N '-Morpholino-N-(2'-Methoxyphenyl)Phthalamide
The apparent second-order rate constant (k(OH)) for hydroxide-ion-catalyzed conversion of 1 to N-(2'-methoxyphenyl)phthalamate (4) is similar to 10(3)-fold larger than k(OH) for alkaline hydrolysis of N-morpholinobenzamide (2). These results are explained in terms of the reaction scheme 1 ->...
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| Format: | Article |
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2008
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