Zinc (II) complex with a cationic Schiff base ligand: Synthesis, characterization, and biological studies

A cationic Schiff base ligand, TSB (L) and its Zn (II) complex (1) were synthesized and characterized by using CHN, 1H-NMR, FT-IR, UV, LC-MS, and X-ray methods. Their ability to inhibit topoisomerase I, DNA cleavage activities, and cytotoxicity were studied. X-ray diffraction study shows that the mo...

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Bibliographic Details
Main Authors: Lee, S.K., Tan, K.W., Ng, S.W., Ooi, K.K., Ang, K.P., Abdah, M.A.
Format: Article
Published: 2013
Subjects: