Boldine improves endothelial function in diabetic db/db mice through inhibition of angiotensin II mediated BMP4 oxidative stress cascade
BACKGROUND AND PURPOSE: Boldine is a potent natural antioxidant present in the leaves and bark of the Chilean boldo tree. Here we assessed the protective effects of boldine on endothelium in a range of models of diabetes, ex vivo and in vitro. EXPERIMENTAL APPROACH: Vascular reactivity was studied i...
| Главные авторы: | , , , , , , , |
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| Формат: | Статья |
| Опубликовано: |
Nature Publishing Group
2013
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| Предметы: |