Analysis of selective metal-salt-induced endotoxin precipitation in plasmid DNA purification using improved LAL assay and central composite design
Recent advancements in plasmid DNA (pDNA) production involve the development of innovative and cost-effective methods as well as reduced number of unit operations. This study investigates the feasibilities of using a metal salt to selectively remove endotoxins from clarified cell lysates containing...
| Main Authors: | , |
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| Format: | Article |
| Language: | English English |
| Published: |
American Chemical Society Publications
2011
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| Subjects: | |
| Online Access: | https://eprints.ums.edu.my/id/eprint/18876/1/Analysis%20of%20selective%20metal.pdf https://eprints.ums.edu.my/id/eprint/18876/7/Analysis%20of%20selective%20metal-salt-induced%20endotoxin%20precipitation%20in%20plasmid%20DNA%20purification%20using%20improved%20LAL%20assay%20and%20central%20composite%20design.pdf |
Internet
https://eprints.ums.edu.my/id/eprint/18876/1/Analysis%20of%20selective%20metal.pdfhttps://eprints.ums.edu.my/id/eprint/18876/7/Analysis%20of%20selective%20metal-salt-induced%20endotoxin%20precipitation%20in%20plasmid%20DNA%20purification%20using%20improved%20LAL%20assay%20and%20central%20composite%20design.pdf