Hunig's base catalyzed synthesis of new 1-(2,3-dihydro-1H-inden-1-yl)-3-aryl urea/ thiourea derivatives as potent antioxidants and 2HCK enzyme growth inhibitors

Hunig's base catalyzed synthesis of new 1-(2,3-dihydro-1H-inden-1-yl)-3-aryl urea/ thiourea derivatives as potent antioxidants and 2HCK enzyme growth inhibitors

A series of 1-(2,3-dihydro-1H-indan-1-yl)-3-aryl urea/thiourea derivatives (4a-j) have been synthesized from the reaction of 2,3-dihydro-1H-inden-1-amine (2) with various aryl isocyanates/isothiocyanates (3a-j) by using N,N-DIPEA base (Hunig's base) catalyst in THF at reflux conditions. All of...

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Bibliographic Details
Main Authors: Venkataramana Lachhi Reddy, Vijay Kumar Reddy Avula, Grigoriy V. Zyryanov, Swetha Vallela, Jaya Shree Anireddy, Visweswara Rao Pasupuleti, Naga Raju Chamarthi
Format: Article
Language:English
Published: 2020
Subjects:
R Medicine (General)
RC Internal medicine
Online Access:https://eprints.ums.edu.my/id/eprint/25099/1/Hunig%27s%20base%20catalyzed%20synthesis%20of%20new%201%20%282%2C3-dihydro%201H%20inden%201%20yl%29%203%20aryl%20urea%20%20thiourea%20derivatives%20as%20potent%20antioxidants%20and%202HCK%20enzyme%20growth%20inhibitors.pdf

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https://eprints.ums.edu.my/id/eprint/25099/1/Hunig%27s%20base%20catalyzed%20synthesis%20of%20new%201%20%282%2C3-dihydro%201H%20inden%201%20yl%29%203%20aryl%20urea%20%20thiourea%20derivatives%20as%20potent%20antioxidants%20and%202HCK%20enzyme%20growth%20inhibitors.pdf

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